Oral s*x is now the leading cause of throat cancer.

A new health pattern is raising alarms
Experts are increasingly warning about a rising link between oral sex and cancers in the throat/neck area, especially oropharyngeal cancer. In both the UK and the US, this type of cancer is being discussed as part of a broader shift in cancer trends, with HPV (human papillomavirus) playing a central role.
What is oropharyngeal cancer?
Oropharyngeal cancer affects the middle part of the throat, including areas such as the tonsils and the back of the tongue. In recent decades, more cases have been associated with HPV infection, rather than traditional causes alone.
Why HPV is at the center of this trend
HPV is widely known for its connection to genital warts, but experts highlight that it can also be linked to certain cancers, including those in the throat.

Key points about HPV:
- HPV includes more than 100 related viruses
- Many infections cause no symptoms and clear naturally
- In some cases, HPV can contribute to wart development or cancer
What experts say is driving the increase
Dr. Hisham Mehanna (University of Birmingham) highlights that the rise of HPV-related throat cancers reflects changes in sexual behavior over the past decades. He notes that HPV has been identified as a primary cause in many modern cases of oropharyngeal cancer.
The role of number of partners
A key risk factor discussed by experts is the number of oral sexual partners over a lifetime.
Reported risk pattern:
- More lifetime oral sexual partners = higher risk
- People with six or more lifetime oral sexual partners are described as being 8.5 times more likely to develop oropharyngeal cancer
Why most people don’t develop cancer from HPV
For most people, the immune system eliminates HPV naturally. However, risk may increase for people whose immune systems struggle to clear the infection.
Higher-risk scenario described by experts:
- If the immune system does not clear HPV, the virus may persist
- Persistent infection may continue to replicate
- Over time, this persistent process may contribute to cancer development
Why this matters now
Experts describe the situation as a growing public health concern because HPV-linked oropharyngeal cancer is becoming more common, especially in Western countries. This change underscores the importance of:
- Awareness of HPV’s link to throat cancers
- Prevention-focused education
- Ongoing research into why some infections persist and become dangerous
Takeaway
The article emphasizes an emerging reality: HPV is increasingly connected to oropharyngeal cancer, and experts believe oral sexual behavior patterns are part of why these cancers are rising in the UK and US. While most infections clear naturally, individuals with persistent HPV infection—especially those with weakened immune defenses—may face a higher risk, making awareness and prevention more important than ever.
